TRULY anti-aging skincare: fine lines, sagging skin, pigment, and pores… IMPROVEMENT in 6 WEEKS!
Hey everyone, welcome back to my channel if this is your first time here, my name is penny
I am a master esthetician in Portland
Oregon and I’m super excited that you’re here today you guys because we are going to talk about some cutting-edge
Skincare now, I’m gonna put it before and after picture up real quick on the screen right here
And I want you to look at this woman’s improvement in a six week time frame
You can definitely see that she has some improvement in her tone and texture
I think you can see that there’s improvement in the laxity of her skin. There’s improvement in her fine lines her wrinkles and just
Kind of an overall skin rejuvenation. I would even say that you can see a little bit better job definitely
Going to talk about today so that product that we’re going to talk about today is the entire line
specifically a few products we’re going to talk about the whole line of
Defin on now you guys have actually asked me to review this you’ve asked about it
I’ve gotten lots and lots of questions about this particular product line, and I was fortunate enough to pick this up at a discount
I did pay for it with my own money, but the doctor that I work with decided to bring this into her practice
So just full transparency here. I did buy this with my own money. I did get it at a discount, but I get no
Commission or kickback or anything like that from this video?
I want you to just stick with me on some of the science because it’s super important
I’m going to nutshell it down for you
but basically when we are in utero what before we are born there is a
Master stem cell that is called LG our sixth positive
We are going to refer to that as the master stem cell for the rest of this video
But that master stem cell is responsible for making us from scratch
it produces all of the skin that what that we have when we are born and then it wraps things up just after birth and
It goes into dormancy in our hair follicle. So that master stem cell then says okay, my work is done
I’ve created this fresh baby full of fresh baby skin
and
Now I’m just going to recede and sit in the hair follicle and wait and the only reason why that master stem cell comes out
to work is if there is a wound so if there is a scratch a scrape a burn a cut
And that master stem cell comes out of dormancy
produces more basal stem cells and those in turn create new skin cells
Okay, so only comes out of dormancy when there is an injury when there’s a wound
the other thing that is really really important to know about this master stem cell and it is really integral to all of this is
That it doesn’t experience age like the rest of the stem cells in our body
This master stem cell is almost like it’s in a time capsule in our hair follicle. It doesn’t experience photo damage
It doesn’t experience mutations anything like that
so when it is asked to come out of dormancy to help heal a wound or a burner or scrape or anything like that it
produces those basal stem cells as
If it were a baby as if it were that fresh kind of skin that has incurred no damage over the course of your life
what is also super important to know is the process that happens in a wound so
Nutshell again when we’re wounded something called a neutrophil is activated this
neutrophil produces something called a defensin
Defensins and I like to think of this almost like like a soap opera
Defensins are the character that is a messenger. There’s been a cut
neutrophils get activated neutrophils produce this little messenger called a defensin and
The defense and carries a little a little note to that master stem cell that we were just talking about and says hey
Can you come help we have a cut up here and we need you to help us fix it
Can you come out of dormancy in that that hair follicle and go to work and the master stem cell says sure
comes out of dormancy goes to work helps heal that wound and
The skin is healed and that is what happens all over our body when we are wounded
There’s a whole wound healing process and collagen gets produced and all that kind of stuff, right?
I mean
That’s why when you’re injured you’re able to heal our body has this whole mechanism in place
And ready so that it can heal itself the company that created
Definis was able to take
Defensins now there they’re synthesized. There is no human product in this product. There’s no animal derived products in this product
So they took defensins and put them in their product
So they basically put that messenger that is only released when there is a wound in to their cream and serum
So that when you put it on topically no wound. There’s no wound
You’d have to put it over any kind of micro needling or dermablend or anything like that
You just put it on morning and night that
Message is being sent down to that master
Stem cell asking it to come produce some fresh skin. It doesn’t know that there hasn’t been a wound
It just knows that it’s been asked to come help and it’s gonna come help. That’s it. So all of that
Sounds very pie-in-the-sky to me
I mean
I don’t know about you
but we hear a lot of claims all the time in skincare and I would say that 90% of the time they’re
Elevated claims they are exaggerated
so what is
Especially exciting about this particular product line is the studies that they did on the products
Now first of all, they started with a pilot study
it was 22 people and basically they got good enough results that they decided to do a
formal study now in this formal study
We are talking double-blind placebo very well controlled study 45 participants
They were all female where the in the pilot study there were men to this absolutely would work for men
Of course in this formal study though, so there were 45 ladies
aged 41 to 71 which is also great in my estimation because those are the people that are the most concerned with
aging it’s those people between
40 and 90 right? I mean that’s the group right there. Okay, they were split into three groups
So there were three centers three sites with three different doctors managing 14 to 16
Ladies at each site now they did of course
Baseline testing and they did testing at six weeks and they did testing at 12 weeks
I think what’s super important about this testing is that it was incredibly objective
It was not just before and after pictures and naked eye kind of assessment of results
They did 3d imaging they did biopsies
they did ultrasound imaging they did the typical where the
investigators at the three different investigators the three different doctors actually obviously also did
Formal assessments with their you know in their experience and that kind of thing, but beyond that they used
devices to get
objective
Results that were measurable. That weren’t just somebody saying. Oh, yes. She looks better
I see less wrinkles. You could measure that there were less wrinkles
You could measure that there was an increase in skin hydration and there was just istic aliy
significant increase in hydration
statistically significant decrease in oiliness
statistically significant improvement in the pores
Which wasn’t expected there were so many fresh new skin cells that they kind of crowded the pores
So the pores appear much more refined because I’ll put there
I’m gonna put a bunch more before-and-afters up as I’m talking you guys, but the appearance of the pores was
Significantly changed in in the positive way
Okay. Also, there was an improvement in trends epidermal waterless
So less water was being lost from our tissue
There was also obviously an improvement in fine lines and improvement in wrinkles. There was an improvement in laxity and
There was also an improvement in pigment
So across the board it was an a statistically significant improvement and it was measured objectively
this study found that
not only did dermal thickness increase in epidermal thickness, which is akin to when we are younger, but it found that it wasn’t due to
inflammation, so if you’ve been here for a while, you know that
Inflammation is pro aging and we don’t want to experience results
That look good, but in fact our inflammation
Which means that down the line we’re going to experience more aging this line is not inflammatory
And that was a huge plus for me
The other thing that I definitely think is worth taking into consideration and possibly researching yourself
Is that growth factors while they are incredibly powerful skincare ingredients?
Everybody can’t use them if you have had cancer in my opinion. You shouldn’t use growth factors
This is not a growth factor
It is a signaling peptide and it has a specific goal to ask that
Master stem cell to go to work to you know, help produce fresh skin
So it isn’t doing what growth factors are doing in effect turning everything on and possibly also
turning on cancer cells so
this product because it’s not a growth factor that just basically stimulates everything is
Potentially much safer for people who have experienced any kind of cancer. I want you to look into that yourself, but that’s definitely
My assessment of this product now
the other thing that I want to point out is that two-thirds of the people in this formal study were
Full formula so they had the products and they had the defense since those
Messenger proteins that were able to ask that master stem cell to go to work
They had everything in the product the people in the SIBO group. So the group that doesn’t have the active ingredient
They had the exact same bottle
They had the exact same formula as the other group only
– those defensins – that signaling peptide everything else in here is the same same smell
same feeling same consistency same other ingredients, so they truly were able to measure the effectiveness of
Defensins in their product. So I think that that’s pretty cool because you you know
You get placebo groups and if you have them just use a moisturizer and the other group is using the full formula
It’s not really it’s apples to oranges
Whereas the placebo group truly was using this product just without those active ingredients the defensins in there
But I want to go through the line and how I’m using it if you’re interested
So first of all, there is a wash. I really like it. I am using this morning and night. It’s kind of a gel consistency
They say to go ahead and put it on dry skin, and then you add water
I actually have found that I really just like to use it traditionally. I put it in in my hand
I add some water and I put it on that way
But it’s a beautiful product and I do find that it removes my makeup, and I’m not double cleansing. I’m just using this
I’m just testing it out and using it that way and I really do like it
So I am doing that now at night I am
Alternating and on one night. I’m going in with my copper peptides and you can see that clearly. I have loved this product
This is the VIP serum from dr. Pickhardt site. I’ve already ordered and received a new
bottle of this
In fact, I like it so much you guys that I purchased the bigger size of this
So I’ll show you what this looks like looks like that I actually do two pumps of this
I probably use too much but I do two pumps of this and I put it all over my face and down my neck and
I don’t really wait any time. I mean, I might wait 10 seconds or something
It soaks, right?
Into my skin and then I go on with a Defen on now the way that you use the definition is a little bit different
Than we’re normally used to
But I put on the 24/7 barrier cream next which is how they advise that you do it
This is actually a cream and it is definitely hydrating and it’s definitely comforting
It’s lightweight, and it kind of soaks in right away, but it feels very very nice on the skin
Now this is obviously backwards than we’re taught and that we’re used to because you do the serum
Next and they do have a really good reason for that. So you wait 30 seconds, and then you do a couple pumps
I’m just gonna do one here of the serum, but you can see it’s kind of almost like a jelly serum
It’s not super thin or anything you put that on over the barrier
Protecting lotion. Now the reason why you do that is in this barrier balance cream
There’s all kinds of antioxidants and all kinds of good stuff in there you put this on first it has less
Defensins in this product. It has less lower concentration of those
messaging peptides in there and that way your skin is able to get
the goods of the antioxidants and all the other things that are in this product if you were to put the serum on
First it is my understanding that
it’s so concentrated with those defensins that it tightens up these junctions in your skin and
The good stuff in here wouldn’t be as accessible to your skin
So they like you to do this first and then you put the serum on over it now there is an eye cream
I’ve been using this eye cream. You put it on your lid
You put it under I find it to be really nice and you don’t need a lot
I put about a half a pump of this eye cream on it does have one of those applicators where you know?
It can get cold and stuff. Honestly, I haven’t used it that way. I’ve literally just gone like this and
Then I you know, put it between my ring finger and I play it all around my eye
Now the one other product that they do have that is really really a great product is their it’s called
Two-minute reveal mask now this is a sugar enzyme mask. It has super super fine grain
Sugar in it and the way that you use this is you actually put this on dry skin a couple times a week
you massage it in on dry skin for about 20 seconds and then you get your fingers wet and the sugar just
Dissolves so you get this manual very fine exfoliation. Then there are enzymes in here
so there’s papaya pumpkin and pomegranate enzymes in this mask and you can leave it on for a couple minutes and you rinse and
Honestly, I’ve had to exercise
I’ve had to restrain myself from you wanting to use this every single day
it’s such a beautiful little mask and it leaves your skin feeling really really soft and smooth and
So you can see what it looks like so I can feel right. Now this very very fine. Grit it is not
SuperDuper scratchy or anything, but it definitely does do a little bit of manual exfoliation
And so if you’re somebody that likes that but as soon as you get your fingers wet
You literally just that sugar dissolves and it turns into this mask
It rinses easily and I really really am enjoying that very very much
None of these products have fragrance some of the products before did have fragrance
So if you decide you want to get this
Just make sure you look and you choose the one without fragrance because I will tell you in the products that do contain fragrance
The fragrance is very very strong and off-putting. I didn’t care for it
The fray the lack of fragrance and these the scents just fine. So that is what I am doing at night on
Alternating nights. I am still using my retinal Dena retinaldehyde from osmosis. I just really like the retinaldehyde from osmosis
I still want to get my vitamin A in my regimen now. My morning time is actually very very similar
I’m kind of doing exactly the same thing and on alternating days
I’m using copper peptides and then on other days I’m fitting in vitamin C in
That very first step like I did with the copper peptide
I just kind of rotate through as
needed and kind of assess my skin if I feel like I need a little bit more of a glow I need a boost I
Will use some vitamin C and then I just go on with the definite now, of course during the day
I am using a moisturizer. I am still using my S clinical the reparative moisture emulsion. I’m still in love with that
I think it’s fantastic
And I just have to be careful not to use that on the days that I use vitamin C because it has copper peptides
So, you know, there’s always the skincare puzzle that you’re trying to make sure you’re not ever using something that you know
You can’t use otherwise and then of course I’m finishing with
Not only my Victoria Beckham of the cell rejuvenating moisturizer, which I’m really enjoying but also my SPF, of course
Which is still the dermatology, so that’s what I’m doing there during the day
I hope you enjoyed this skincare breakdown and I hope you share my excitement check the description box
Really? There’s not gonna be any affiliate links for this product line
I am NOT linking it to make a commission or anything like that
You are welcome to contact the office where I work and ask for more information
They do sell it and they do ship if you’re interested and again
Absolutely, no affiliation personally or kickback on my end
But you can get more information and know that you’re getting a legitimate product, etc
I will put that information in the description box for sure
I hope you guys are having a fantastic week and I will talk to you in my next skincare video. Take care
